Some methodological problems of the optimization of microecological risk factors to health

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In order to prevent the phenomena of “microbiological genocide”, unjustified and unfavorable violations in microecological systems, and, first of all, human microbiota during the implementation of the disinfection prevention of diseases, the necessity for the scientific justification and practical provision of sufficient antimicrobial selectivity of disinfecting effects, is substantiated in the article. It is necessary to decode and take into account the susceptibility of different microbe pathogens to various disinfectants in comparison with saprophyte, and even more so, useful microflora.

Sobre autores

Mikhail Shandala

Research Institute of Disinfectology of the Federal Service on Customers’ Rights Protection and Human Well-Being Surveillance; I.M. Sechenov First Moscow State Medical University

Autor responsável pela correspondência
Email: info@niid.ru

MD, Ph.D., DSci.,  Academician of the Russian Academy of Sciences, Professor, Chief Researcher of the Research Institute of Disinfectology Federal Agency for Social Protection of the Russian Academy of Medical Sciences, 117246, Moscow, Scientific passage, 18; Professor of the Department of Disinfectology of the First Moscow State Medical University. THEM. Sechenov of the Ministry of Health of Russia.

e-mail: info@niid.ru

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Bibliografia

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  2. Pokrovskiy V.I., Muratov V.K. Chemoprophylaxis. Chemotherapeutic agents. Chemotherapy. Great medical encyclopedia. In: Soviet Encyclopedia. Volume 26 [Sovetskaya entsiklopediya. Tom 26]. Moscow; 1985: 502-6. (in Russian)
  3. Shandala M.G. Creation of a unified system of antimicrobial and microbial protection as an actual hygienic problem. Gigiena i sanitariya. 2015; 94(8): 5-7. (in Russian)
  4. Shaposhnikova L.I. Human microbiota as the main physiological organ. Uspekhi sovremennogo estestvoznaniya. 2006; (9): 80-2. (in Russian)
  5. Bondarenko V.M., Rybal’chenko O.V. Analysis of the preventive and curative effect of probiotic drugs from the standpoint of new scientific technologies. Zhurnal mikrobiologii, epidemiologii i immunobiologii. 2015; (2): 90-104. (in Russian)
  6. Shestopalov N.V., Shandala M.G. Biopathogens as a significant risk factor for health and their control in the environment, or disinfection risks “in the noble cause” of combating infectious diseases. Analiz riska zdorov’yu. 2014; (4): 14-9. (in Russian)
  7. World Gastroenterology Organisation Global Guidelines. Probiotics and prebiotics. Available at: http://www.worldgastroenterology.org/UserFiles/file/guidelines/probiotics-english-2011.pdf
  8. Shestopalov N.V., Shandala M.G. Molecular-biological aspects of disinfection: state and tasks of in-depth development. Dezinfektsionnoe delo. 2013; (3): 17-21. (in Russian)
  9. Shestopalov N.V., Shandala M.G. Disinfectology as a molecular-epidemiological direction of the fight against infections. Zhurnal mikrobiologii, epidemiologii i immunobiologii. 2014; (1): 66-70. (in Russian)
  10. Shandala M.G. Questions of selective toxicity in the problem of the safety of disinfectants. Dezinfektsionnoe delo. 2013; (1): 14-7. (in Russian)

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