Carcino-evo-devo: Rule or Exception? Review of the Series of A. P. Kozlov Articles in the Journal “Advances in Current Biology”

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详细

Igor V. Mizgirev, PhD, senior researcher of the Petrov National Medical Research Center of Oncology of the Ministry of Health of the Russian Federation provides a feedback on the series of articles published in the journal «Advances in current biology» of the Russian Academy of Sciences in 2024, in which he notes that the concept of carcino-evo-devo, developed by professor A.P. Kozlov over several decades, represents a new approach to understanding the possible role of pathological processes in the evolution of living organisms. This approach is based on the idea of hereditary tumors with small malignant potential (benign and malignant in the early stages of progression), as a kind of testing grounds, where new genes that have arisen in the course of evolution are able to be expressed in excess cell masses, and, eventually, lead to the formation of new types of cells, tissues and organs.

作者简介

I. Mizgirev

Petrov National Medical Research Center of Oncology, Ministry of Health of the Russian Federation

编辑信件的主要联系方式.
Email: ivm1530@gmail.com
St. Petersburg, Russia

参考

  1. Козлов А.П. Теория эволюционной роли наследуемых опухолей (carcino-evo-devo): история развития и современное состояние. Часть 1. От общих принципов к гипотезе и от гипотезы к концепции // Успехи соврем. биол. 2024а. Т. 144 (3). С. 249–264. https://doi.org/10.31857/S0042132424030013
  2. Козлов А.П. Теория эволюционной роли наследуемых опухолей (carcino-evo-devo): история развития и современное состояние. Часть 2. Становление теории в книге “Evolution by tumor neofunctionalization” // Успехи соврем. биол. 2024б. Т. 144 (4). С. 364–373. https://doi.org/10.31857/S0042132424040011
  3. Козлов А.П. Теория эволюционной роли наследуемых опухолей (carcino-evo-devo): история развития и современное состояние. Часть 3. Современное состояние теории carcino-evo-devo и ее взаимоотношения с другими биологическими науками // Успехи соврем. биол. 2024в. Т. 144 (4). С. 374–401. https://doi.org/10.31857/S0042132424040024
  4. Козлов А.П. Теория эволюционной роли наследуемых опухолей (carcino-evo-devo): история развития и современное состояние. Часть 4. Общая теория увеличения биологической сложности в прогрессивной эволюции // Успехи соврем. биол. 2024г. Т. 144 (5). С. 478–487. https://doi.org/10.31857/S0042132424050011
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