Medical and Social Expert Evaluation and RehabilitationMedical and Social Expert Evaluation and RehabilitationМедико-социальная экспертиза и реабилитация1560-95372412-2092Eco-Vector3425910.17816/MSER34259ArticlesСтатьиResearch ArticleStatistics of melanoma in Russia and EuropeСтатистика меланомы в России и странах ЕвропыErkenovaFatima D.ЭркеноваФатима Джамбулатовна
Russian Federation
erkenova07@gmail.comPuzinS. N.ПузинСергей Никифорович

д.м.н., проф., академик РАН, заведующий кафедрой гериатрии и медико-социальной экспертизы; заместитель директора по науке

s.puzin2012@yandex.ruI. M. Sechenov first Moscow state medical University (Sechenov University)Первый Московский государственный медицинский университет им. И.М. Сеченова (Сеченовский университет) Минздрава РоссииFederal Scientific and Clinical Center of Reanimatology and RehabilitationФГБНУ «Федеральный научно-клинический центр реаниматологии и реабилитологии»Russian Medical Academy of Continuing Professional EducationФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования» Минздрава России1508202023144523105202008062020Copyright ©; 2020, Eco-VectorCopyright ©; 2020, ООО "Эко-Вектор"2020Eco-VectorООО "Эко-Вектор"https://rjmseer.com/1560-9537/article/view/34259

The article considers the laws of the epidemic process of skin melanoma in Russia and European countries over the past half-century. Attention is given to the sharp increase in incidence worldwide, and, particularly in Russia. Increasing incidence occurs mainly due to the popularization of outdoor recreation, the fashion for intense tan and frequent tourist trips to mountainous regions and tropical countries. Early diagnosis and prevention are the main measures for reducing the growth of morbidity and mortality from skin melanoma.

В статье рассматриваются закономерности эпидемического процесса меланомы кожи в России и странах Европейского региона за последние годы. Обращается внимание на резкое увеличение заболеваемости по всему миру и в России в частности. Повышение заболеваемости происходит в основном из-за популяризации отдыха на открытом воздухе, моды на интенсивный загар, а также участившихся туристических поездок в горные районы и тропические страны. Ранняя диагностика и профилактика остаются главными мерами снижения роста заболеваемости и смертности от меланомы кожи.

skin cancermelanomaepidemiologyрак кожимеланомаэпидемиологияLinos E, Swetter SM, Cockburn MG, et al. Increasing burden of melanoma in the United States. J Investig Dermatol. 2009;129(7):1666−1674. https://doi.org/10.1038/jid.2008.423.Surveillance, Epidemiology, and End Results (SEER). Program Cancer Statistics Review, 1975–2013, National Cancer Institute [Internet]. Nov, 2015. Available from: https://seer.cancer.gov/archive/csr/1975_2013/Erdei E, Torres SM. A new understanding in the epidemiology of melanoma. Exp Rev Anticancer Ther. 2010;10(11):1811−1823. https://doi.org/10.1586/era.10.170.Rigel DS, Carucci JA. Malignant melanoma: Prevention, early detection, and treatment in the 21st century. CA Cancer J Clin. 2000;50(4):215−236. https://doi.org/10.3322/canjclin.50.4.215.Ferlay J, Soerjomataram I, Ervik M, et al., ed. by. GLOBOCAN 2012 v 1.0, Cancer Incidence and Mortality Worldwide: IARC CancerBase No. 11 [Internet]. Available from: https://publications.iarc.fr/Databases/Iarc-Cancerbases/GLOBOCAN-2012-Estimated-Cancer-Incidence-Mortality-And-Prevalence-Worldwide-In-2012-V1.0-2012.Kosary CL, Altekruse SF, Ruhl J, et al. Clinical and prognostic factors for melanoma of the skin using SEER registries: Collaborative stage data collection system, version 1 and version 2. Cancer. 2014;120(Suppl 23):3807−3814. https://doi.org/10.1002/cncr.29050.Guy GP, Thomas CC, Thompson T, et al. Vital signs: Melanoma incidence and mortality trends and projections ― United States, 1982–2030. MMWR Morb Mortal Wkly Rep. 2015;64(21):591−596.Califano J, Nance M. Malignant melanoma. Facial Plast Surg Clin North Am. 2009;17(3):337−348. https://doi.org/10.1016/j.fsc.2009.05.002.Starinskiy VV, Kaprin AD, Petrova GYu. Zlokachestvennyye novoobrazovaniya v Rossii v 2012 g. (zabolevayemost’ i smertnost’). Moscow: MNIOI im. P.A. Gertsena; 2014. 250 р. (In Russ).Старинский В.В., Каприн А.Д., Петрова Г.Ю. Злокачественные новообразования в России в 2012 г. (заболеваемость и смертность). ― М.: МНИОИ им. П. А. Герцена, 2014. ― 250 с.Chissov VI, Starinskiy VV, Petrova GYu. Zlokachestvennyye novoobrazovaniya v Rossii v 2001 g. (zabolevayemost’ i smertnost’). Moscow: MNIOI im. P.A. Gertsena; 2003. 240 р. (In Russ).Чиссов В. И., Старинский В. В., Петрова Г. Ю. Злокачественные новообразования в России в 2001 г. (заболеваемость и смертность). ― М.: МНИОИ им. П. А. Герцена, 2003. ― 240 с.Kungurov NV, Malishevskaya NP, Kokhan MM, Iglikov VA. Epidemiologiya zlokachestvennykh novoobrazovaniy kozhi na Srednem Urale. Zlokachestvennyye novoobrazovaniya kozhi: zabolevayemost’, oshibki diagnostiki, organizatsiya rannego vyyavleniya, profilaktika. Kurgan: Zaural’ye; 2010. Р. 8−33. (In Russ).Кунгуров Н.В., Малишевская Н.П., Кохан М.М., Игликов В.А. Эпидемиология злокачественных новообразований кожи на Среднем Урале. Злокачественные новообразования кожи: заболеваемость, ошибки диагностики, организация раннего выявления, профилактика. ― Курган: Зауралье, 2010. ― С. 8−33.Chao LX, Patterson SS, Rademaker AW, et al. Melanoma perception in people of color: A targeted educational intervention. Am J Clin Dermatol. 2017;18(3):419−427. https://doi.org/10.1007/s40257-016-0244-y.Brenner M, Hearing VJ. The protective role of melanin against UV damage in human skin. Photochem Photobiol. 2008;84(3):539−549. https://doi.org/10.1111/j.1751-1097.2007.00226.x.Everett MA, Yeargers E, Sayre RM, Olson RL. Penetration of epidermis by ultraviolet rays. Photochem Photobiol. 1966;5(7):533−542. https://doi.org/10.1111/j.1751-1097.1966.tb09843.x.Grigalavicius M, Moan J, Dahlback A, Juzeniene A. Daily, seasonal, and latitudinal variations in solar ultraviolet A and B radiation in relation to vitamin D production and risk for skin cancer. Int J Dermatol. 2016;55(1):e23−28. https://doi.org/10.1111/ijd.13065.Seebode C, Lehmann J, Emmert S. Photocarcinogenesis and skin cancer prevention strategies. Anticancer Res. 2016;36(3):1371−1378.Moan J, Grigalavicius M, Baturaite Z, et al. The relationship between UV exposure and incidence of skin cancer. Photodermatol Photoimmunol Photomed. 2015;31(1):26−35. https://doi.org/10.1111/phpp.12139.Li WQ, Cho E, Weinstock MA, et al. Epidemiological assessments of skin outcomes in the nurses’ health studies. Am J Public Health. 2016;106(9):1677−1683. https://doi.org/10.2105/AJPH.2016.303315.Qureshi AA, Laden F, Colditz GA, Hunter DJ. Geographic variation and risk of skin cancer in US women. Differences between melanoma, squamous cell carcinoma, and basal cell carcinoma. Arch Intern Med. 2008;168(5):501−507. https://doi.org/10.1001/archinte.168.5.501.Wu S, Han J, Laden F, Qureshi AA. Long-term ultraviolet flux, other potential risk factors, and skin cancer risk: A cohort study. Cancer Epidemiol Biomark Prev. 2014;23(6):1080−1089. https://doi.org/10.1158/1055-9965.EPI-13-0821.Wu S, Han J, Vleugels RA, et al. Cumulative ultraviolet radiation flux in adulthood and risk of incident skin cancers in women. Br J Cancer. 2014;110(7):1855−1861. https://doi.org/10.1038/bjc.2014.43.Green A. A theory of site distribution of melanomas: Queensland, Australia. Cancer Causes Control. 1992;3(6):513−516. https://doi.org/10.1007/BF00052747.Matthews NH, Li WQ, Qureshi AA, Martin A. Weinstock. In: Ward WH, Farma JM, editors. Cutaneous Melanoma: Etiology and Therapy. Codon Publications; 2017. 21 р.Li WQ, Qureshi AA, Ma J, et al. Personal history of prostate cancer and increased risk of incident melanoma in the United States. J Clin Oncol. 2013;31(35):4394−4399. https://doi.org/10.1200/JCO.2013.51.1915.Elder DE. Human melanocytic neoplasms and their etiologic relationship with sunlight. J Investig Dermatol. 1989;92(5 Suppl):297S−303S. https://doi.org/10.1111/1523-1747.ep13076732.Coory M, Baade P, Aitken J, et al. Trends for in situ and invasive melanoma in Queensland, Australia, 1982–2002. Cancer Causes Control. 2006;17(1):21−27. https://doi.org/10.1007/s10552-005-3637-4.MacKie RM, Bray CA, Hole DJ, et al. Incidence of and survival from malignant melanoma in Scotland: An epidemiological study. Lancet. 2002;360(9333):587−591. https://doi.org/10.1016/S0140-6736(02)09779-9.Watson M, Geller AC, Tucker MA, et al. Melanoma burden and recent trends among non-Hispanic whites aged 15–49 years, United States. Prev Med. 2016;91:294−298. https://doi.org/10.1016/j.ypmed.2016.08.032.Garbe C, Leiter U. Melanoma epidemiology and trends. Clin Dermatol. 2009;27(1):3−9. https://doi.org/10.1016/j.clindermatol.2008.09.001.Weir HK, Marrett LD, Cokkinides V, et al. Melanoma in adolescents and young adults (ages 15–39 years): United States, 1999–2006. J Am Acad Dermatol. 2011;65(5 Suppl 1):S38−49. https://doi.org/10.1016/j.jaad.2011.04.038.Zhang M, Qureshi AA, Geller AC, et al. Use of tanning beds and incidence of skin cancer. J Clin Oncol. 2012;30(14):1588−1593. https://doi.org/10.1200/JCO.2011.39.3652.Osterlind A, Hou-Jensen K, Moller Jensen O. Incidence of cutaneous malignant melanoma in Denmark 1978–1982. Anatomic site distribution, histologic types, and comparison with non-melanoma skin cancer. Br J Cancer. 1988;58(3):385−391. https://doi.org/10.1038/bjc.1988.225.Magnus K. Habits of sun exposure and risk of malignant melanoma: an analysis of incidence rates in Norway 1955–1977 by cohort, sex, age, and primary tumor site. Cancer. 1981;48(10):2329−2335. https://doi.org/10.1002/1097-0142(19811115)48:10<2329::aid-cncr2820481032>3.0.co;2-o.Popescu NA, Beard CM, Treacy PJ, et al. Cutaneous malignant melanoma in Rochester, Minnesota: Trends in incidence and survivorship, 1950 through 1985. Mayo Clinic Proc. 1990;65:(10):1293−1302. https://doi.org/10.1016/s0025-6196(12)62140-5.Masback A, Westerdahl J, Ingvar C, et al. Cutaneous malignant melanoma in south Sweden 1965, 1975, and 1985. A histopathologic review. Cancer. 1994;73(6):1625−1630. https://doi.org/10.1002/1097-0142(19940315)73:6<1625::aid-cncr2820730614>3.0.co;2-#.Cho E, Rosner BA, Colditz GA. Risk factors for melanoma by body site. Cancer Epidemiol Biomarkers Prev. 2005;14(5):1241−1244. https://doi.org/10.1158/1055-9965.EPI-04-0632.Stierner U, Augustsson A, Rosdahl I, Suurkula M. Regional distribution of common and dysplastic naevi in relation to melanoma site and sun exposure. A case-control study. Melanoma Res. 1992;1(5–6):367−375. https://doi.org/10.1097/00008390-199201000-00008.Green A, MacLennan R, Youl P, Martin N. Site distribution of cutaneous melanoma in Queensland. Int J Cancer. 1993;53(2):232−236. https://doi.org/10.1002/ijc.2910530210.Lachiewicz AM, Berwick M, Wiggins CL, Thomas NE. Epidemiologic support for melanoma heterogeneity using the surveillance, epidemiology, and end results program. J Investig Dermatol. 2008;128(5):1340−1342. https://doi.org/10.1038/jid.2008.18.Stang A, Stabenow R, Eisinger B, Jockel KH. Site- and gender-specific time trend analyses of the incidence of skin melanomas in the former German Democratic Republic (GDR) including 19351 cases. Eur J Cancer. 2003;39:(11):1610−1618. https://doi.org/10.1016/s0959-8049(03)00359-9.Elwood JM, Gallagher RP. Body site distribution of cutaneous malignant melanoma in relationship to patterns of sun exposure. Int J Cancer. 1998;78(3):276−280. https://doi.org/10.1002/(SICI)1097-0215(19981029)78:3<276::AID-IJC2>3.0.CO;2-S.Perez-Gomez B, Aragones N, Gustavsson P, et al. Do sex and site matter? Different age distribution in melanoma of the trunk among Swedish men and women. Br J Dermatol. 2008;158(4):766−772. https://doi.org/10.1111/j.1365-2133.2007.08429.x.Stratigos A, Nikolaou V, Kedicoglou S, et al. Melanoma/skin cancer screening in a Mediterranean country: results of the Euromelanoma screening day campaign in Greece. J Eur Acad Dermatol Venereol. 2007;21(1):56−62. https://doi.org/10.1111/j.1468-3083.2006.01865.x.Kaprin AD, Starinskiy VV, Petrova GV. Malignancies in Russia in 2014 (morbidity and mortality). Moscow: RIIS FIAN; 2015. 249 р. (In Russ).Paoli J, Danielsson M, Wennberg AM. Results of the ‘Euromelanoma Day’screening campaign in Sweden 2008. J Eur Acad Dermatol Venereol. 2009;23:(11):1304−1310. https://doi.org/10.1111/j.1468-3083.2009.03316.x.Kiellberg LH, Sand C. Referral pattern of skin diseases in an acute outpatient dermatological clinic in Copenhagen. Acta Derm Venereol. 2005;85:(6):509−511. https://doi.org/10.1080/00015550510034957.Motorina AV, Palkina NV, Komina AV, et al. Genetic analysis of melanocortin 1 receptor red hair color variants in Russian population of Eastern Siberia. Eur J Cancer Prev. 2018;27(2):192−196. https://doi.org/10.1097/CEJ.0000000000000317.Tucker MA, Halpern A, Holly EA, et al. Clinically recognized dysplastic nevi. A central risk factor for cutaneous melanoma. JAMA. 1997;277(18):1439−1444.