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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Medical and Social Expert Evaluation and Rehabilitation</journal-id><journal-title-group><journal-title xml:lang="en">Medical and Social Expert Evaluation and Rehabilitation</journal-title><trans-title-group xml:lang="ru"><trans-title>Медико-социальная экспертиза и реабилитация</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1560-9537</issn><issn publication-format="electronic">2412-2092</issn><publisher><publisher-name xml:lang="en">Eco-Vector</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">35845</article-id><article-id pub-id-type="doi">10.17816/MSER35845</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Effect of weight loss on erectile function and quality of life in obese men</article-title><trans-title-group xml:lang="ru"><trans-title>Влияние снижения массы тела на эректильную функцию и качество жизни у мужчин с ожирением</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Ametov</surname><given-names>A. S</given-names></name><name xml:lang="ru"><surname>Аметов</surname><given-names>А. С</given-names></name></name-alternatives><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Doskina</surname><given-names>E. V</given-names></name><name xml:lang="ru"><surname>Доскина</surname><given-names>Е. В</given-names></name></name-alternatives><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Stelmakh</surname><given-names>Mariya V.</given-names></name><name xml:lang="ru"><surname>Стельмах</surname><given-names>Мария Владимировна</given-names></name></name-alternatives><bio xml:lang="en"><p>MD</p></bio><bio xml:lang="ru"><p>аспирант каф. эндокринологии и диабетологии</p></bio><email>mariastel@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Russian Medical Academy of Postgraduate Education</institution></aff><aff><institution xml:lang="ru">ГБОУ ДПО «Российская медицинская академия последипломного образования» Минздрава России</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2014-12-15" publication-format="electronic"><day>15</day><month>12</month><year>2014</year></pub-date><volume>17</volume><issue>4</issue><issue-title xml:lang="en">VOL 17, NO4 (2014)</issue-title><issue-title xml:lang="ru">ТОМ 17, №4 (2014)</issue-title><fpage>49</fpage><lpage>52</lpage><history><date date-type="received" iso-8601-date="2020-07-21"><day>21</day><month>07</month><year>2020</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2014, Eco-Vector</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2014, ООО "Эко-Вектор"</copyright-statement><copyright-year>2014</copyright-year><copyright-holder xml:lang="en">Eco-Vector</copyright-holder><copyright-holder xml:lang="ru">ООО "Эко-Вектор"</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/" start_date="2025-01-01"/></permissions><self-uri xlink:href="https://rjmseer.com/1560-9537/article/view/35845">https://rjmseer.com/1560-9537/article/view/35845</self-uri><abstract xml:lang="en"><p>In recent years there has been a sharp increase in the prevalence of obesity in the world that stimulate interest in the effects on health and quality of life of the phenomenon. In developed countries, obesity is considered the fifth most significant riskfactorfor disability. Quality of life of obese patients is an important issue that must be considered more carefully. Unfortunately, not enough studied the effect weight loss on sexual function and quality of life. Consequently, the aim of our study was to - to study the effect of weight loss on erectile function and quality of life in men with obesity. The study involved 40 men aged 30 to 50 years, mean age 43,4 ± 7,5, BMI 40,4 ± 7. At the initial ethane we measured anthropometric indicators, questionnaires using the International Index of Erectile Function-5, Hospital Anxiety and Depression Scale, the Russian version of the general questionnaire MOS-SF-36 (MOSSF-Item Short Form Health Survey). Further, all patients received sibutramine 10-15 mg (Reduxine, Promo-Med) on a par with changing lifestyles within 6 months. We have found that with the increase in severity of erectile function were growing anxiety symptoms (r = 0,521; p &lt; 0,05) and depression (r = 0,593; p &lt; 0,01). After weight loss the patients’ quality of life significantly improved in terms ofpsychological health, as well as indicators ofviability and role emotional functioning. Conclusions: Obesity reduces the quality of life ofpatients, leading to the development of erectile dysfunction, depression and anxiety, moderate weight loss is largely due to the improved quality of life, erectile function, decrease symptoms of anxiety/depression.</p></abstract><trans-abstract xml:lang="ru"><p>В последние годы наблюдается резкий рост распространенности ожирения во всем мире, что стимулирует интерес к последствиям для здоровья и качества жизни этого явления. В развитых странах ожирение уже считается пятым самым серьезным фактором риска инвалидности и одной из основных причин нетрудоспособности. Качество жизни пациентов, страдающих ожирением, является важным вопросом, который должен быть рассмотрен более тщательно. К сожалению, недостаточно изучено как влияет снижение массы тела на сексуальную функцию и качество жизни. Следовательно, целью нашего исследования стало изучение влияния снижения массы тела на эректильную функцию и качество жизни у мужчин с ожирением. В исследовании принимало участие 40 мужчин в возрасте от 30 до 50 лет (средний возраст 43,4 ± 7,5 года, индекс массы тела 40,4 ± 7). На начальном этане проводилось определение антропометрических показателей, анкетирование с помощью Международного индекса эректильной функции-5, Госпитальной шкалы тревоги и депрессии, русской версии общего опросника MOS-SF-36 (MOSSF-Item Short Form Health Survey). Далее все пациенты получали сибутрамин 10-15 мг (редуксин, Промо-Мед) наравне с изменением образа жизни в течение 6 мес. Нами было выявлено, что с нарастанием степени тяжести эректильной функции нарастали симптомы тревоги (r = 0,521; р &lt; 0,05) и депрессии (r = 0,593; р &lt; 0,01). После снижения массы тела достоверно повысилось качество жизни пациентов по показателям психологического здоровья, а также показателям жизнеспособности и ролевого эмоционального функционирования. Выводы: ожирение снижает качество жизни пациентов, приводит к развитию эректильной дисфункции, депрессии и тревоге; умеренная потеря массы тела в значительной степени связана с улучшением качества жизни, эректильной функции, снижением симптомов тревоги/депрессии.</p></trans-abstract><kwd-group xml:lang="en"><kwd>obesity</kwd><kwd>erectile dysfunction</kwd><kwd>quality of life</kwd><kwd>sibutramine</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>ожирение</kwd><kwd>эректильная дисфункция</kwd><kwd>качество жизни</kwd><kwd>сибутрамин</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Flegal K.M., Carroll M.D., Ogden C.L., Johnson C.L. Prevalence and trend in obesity among US adults, 1999-2000. J. A. M. A. 2002; 288: 1723-7.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>WHO. Diet, Nutrition and the Prevention of Chronic Diseases. Report of a Joint WHO/FAO Expert Consultation. 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