Interaction of the Bipyridyl Gold(III) Complex with Anions of Thiol-Containing Acids in Aqueous Solution

I. V. Mironov; Миронов И. В.; V. Yu. Kharlamova; Харламова В. Ю.; J. Hu; Ху Ц.

doi:10.31857/S0044457X22601651

Interaction of the Bipyridyl Gold(III) Complex with Anions of Thiol-Containing Acids in Aqueous Solution

Authors: Mironov I.V.¹, Kharlamova V.Y.¹, Hu J.²
Affiliations:
1. Nikolaev Institute of Inorganic Chemistry, Siberian Branch, Russian Academy of Sciences
2. Novosibirsk State University
Issue: Vol 68, No 3 (2023)
Pages: 342-348
Section: ФИЗИКОХИМИЯ РАСТВОРОВ
URL: https://rjmseer.com/0044-457X/article/view/665287
DOI: https://doi.org/10.31857/S0044457X22601651
EDN: https://elibrary.ru/JDZGEF
ID: 665287

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Abstract

The equilibria of stepwise substitution Au(bipy)
+ OH– = Au(bipy)ClOH+ + Cl– and Au(bipy)
+ 2OH– = Au(bipy)
+ 2Cl– in aqueous solution at T = 25°C and I = 0.2 M (NaCl), log β1 = 9.22, log β2 = 16.61 have been studied. For bipyridyl complexes Au(bipy)
(X = Cl, OH) at pH 2.0 and 7.4, redox interactions with anions of thiol-containing acids (glutathione, cysteine, thiomalate) have been studied. In all cases, at the initial stage, a rapid reduction of gold(III) to gold(I) was observed with the simultaneous release of bipyridyl. A detailed analysis of UV spectra showed that the main products of gold(III) reduction are highly stable gold(I) thiolate complexes. The presence of further slower steps depends on the initial ratio of thiol to gold.

Keywords

nitrogen-containing ligands, complexation, glutathione, cysteine, thiomalate

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