Synthesis and phosphonylation of S-methylthiouracil and its derivatives

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Abstract

A series of S -methylated derivatives of 2-thiouracil were prepared and then phosphonylated with diethyl chlorophosphate. The reaction conditions were optimized, the structure of the obtained compounds was determined by 1Н, 13С, 31Р NMR spectroscopy methods.

About the authors

A. S Skrylkova

St. Petersburg State Institute of Technology (Technical University)

N. A Nosova

St. Petersburg State Institute of Technology (Technical University)

D. M Egorov

St. Petersburg State Institute of Technology (Technical University)

Email: diavoly@mail.ru

M. D Khalikova

V.I. Nikitin Institute of Chemistry, National Academy of Sciences of Tajikistan

U. A Rozikov

V.I. Nikitin Institute of Chemistry, National Academy of Sciences of Tajikistan

S. Sh. Safarov

V.I. Nikitin Institute of Chemistry, National Academy of Sciences of Tajikistan

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