Lipoxygenase in a giant sulfur bacterium: an evolutionary solution for size and complexity?

Cover Page

Cite item

Full Text

Open Access Open Access
Restricted Access Access granted
Restricted Access Subscription Access

Abstract

Discovery of Thiomargarita magnifica - an exceptionally large giant sulfur bacterium - urges us to pay additional attention to the giant sulfur bacteria and to revisit our recent bioinformatic finding of lipoxygenases in the representatives of the genus Beggiatoa. These close relatives of Thiomargarita magnifica meet the similar size requirements by forming multicellular structures. We hypothesize that their lipoxygenases are a part of the oxylipin signaling system that provides high level of cell-to-cell signaling complexity which, in turn, enables them to reach large sizes.

About the authors

G. F Kurakin

Pirogov Russian National Research Medical University

Email: georgykurakin@gmail.com
117997 Moscow, Russia

References

  1. Kurakin, G. F., Samoukina, A. M., and Potapova, N. A. (2020) Bacterial and Protozoan lipoxygenases could be involved in cell-to-cell signaling and immune response suppression, Biochemistry (Moscow), 85, 1048-1063, doi: 10.1134/S0006297920090059.
  2. Andreou, A. Z., Vanko, M., Bezakova, L., and Feussner, I. (2008) Properties of a mini 9R-lipoxygenase from Nostoc sp. PCC 7120 and its mutant forms, Phytochemistry, 69, 1832-1837, doi: 10.1016/j.phytochem.2008.03.002.
  3. Lang, I., G�bel, C., Porzel, A., Heilmann, I., and Feussner, I. (2008) A lipoxygenase with linoleate diol synthase activity from Nostoc sp. PCC 7120, Biochem. J., 410, 347-357, doi: 10.1042/BJ20071277.
  4. An, J. U., Hong, S. H., and Oh, D. K. (2018) Regiospecificity of a novel bacterial lipoxygenase from Myxococcus xanthus for polyunsaturated fatty acids, Biochim. Biophys. Acta Mol. Cell Biol. Lipids, 1863, 823-833, doi: 10.1016/j.bbalip.2018.04.014.
  5. Vance, R. E., Hong, S., Gronert, K., Serhan, C. N., and Mekalanos, J. J. (2004) The opportunistic pathogen Pseudomonas aeruginosa carries a secretable arachidonate 15-lipoxygenase, Proc. Natl. Acad. Sci. USA, 101, 2135-2139, doi: 10.1073/pnas.0307308101.
  6. Morello, E., P�rez-Berezo, T., Boisseau, C., Baranek, T., Guillon, A., Br�a, D., Lanotte, P., Carpena, X., Pietrancosta, N., Herv�, V., Ramphal, R., Cenac, N., and Si-Tahar, M. (2019) Pseudomonas aeruginosa lipoxygenase LoxA contributes to lung infection by altering the host immune lipid signaling, Front. Microbiol., 10, 1826, doi: 10.3389/fmicb.2019.01826.
  7. Salman, V., Bailey, J. V. and Teske, A. (2013) Phylogenetic and morphologic complexity of giant sulphur bacteria, Antonie van Leeuwenhoek, 104, 169-186, doi: 10.1007/s10482-013-9952-y.
  8. J�rgensen, B. (2010) Big sulfur bacteria, ISME J., 4, 1083-1084, doi: 10.1038/ismej.2010.106.
  9. Teske, A., and Nelson, D. C. (2006) in The Prokaryotes (Dworkin, M., Falkow, S., Rosenberg, E., Schleifer, K.-H., and Stackebrandt, E., eds) Springer, N. Y., pp. 784-810, doi: 10.1007/0-387-30746-X_27.
  10. Chrisnasari, R., Hennebelle, M., Vincken, J. P., van Berkel, W. J., and Ewing, T. A. (2022) Bacterial lipoxygenases: biochemical characteristics, molecular structure and potential applications, Biotechnol. Adv., 61, 108046, doi: 10.1016/j.biotechadv.2022.108046.
  11. Volland, J. M., Gonzalez-Rizzo, S., Gros, O., Tyml, T., Ivanova, N., Schulz, F., Goudeau, D., Elisabeth, N. H., Nath, N., Udwary, D., Malmstrom, R. R., Guidi-Rontani, C., Bolte-Kluge, S., Davies, K. M., Jean, M. R., Mansot, J. L., Mouncey, N. J., Angert, E. R., Woyke, T., and Date, S. V. (2022) A centimeter-long bacterium with DNA contained in metabolically active, membrane-bound organelles, Science, 376, 1453-1458, doi: 10.1126/science.abb3634.
  12. Pennisi, E., Stokstad, E., Gibbons, A., Stone, R., Cohen, J., Savitsky, Z., Voosen, P., Hutson, M., and Kaiser, J. (2022) Runners-up, Science, 378, 1162-1167, doi: 10.1126/science.adg2799.
  13. Schulz, H. N., and Riechmann, D. (2000) Thiomargarita namibiensis: A giant with staying power [in German], BioSpektrum, 6, 116-117.
  14. Schulz, H. N. (2002) Thiomargarita namibiensis: Giant microbe holding its breath, ASM News, 68, 122-127, doi: 10.1128/AEM.68.11.5746-5749.2002.
  15. Kuenen, G. (1999) in Biology of the Prokaryotes (Lengeler, J. W., Drews, G., and Schlegel, H. G., eds) Thieme Stuttgart, N. Y., pp. 234-260, doi: 10.1002/9781444313314.ch10.

Supplementary files

Supplementary Files
Action
1. JATS XML
Download

Copyright (c) 2023 Russian Academy of Sciences