Synthesis of 1-antipyryl-1H-pyrrol-2-ones by interaction N-antipyryl substituted enamines with oxalyl chloride

Capa

Citar

Texto integral

Acesso aberto Acesso aberto
Acesso é fechado Acesso está concedido
Acesso é fechado Acesso é pago ou somente para assinantes

Resumo

Methyl 4-aryl-2-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1 H -pyrazol-4-ylamino)-4-oxo-2-butenoates react with oxalyl chloride to form methyl 3-aroyl-2-chloro-1-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1 H -pyrazol-4-yl)-4-hydroxy-5-oxo-2, 5-dihydro-1 H -pyrrole-2-carboxylates, which are hydrolyzed to methyl 3-aroyl1-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1 H -pyrazol-4-yl)-2,4-dihydroxy-5-oxo-2,5-dihydro-1 H -pyrrole2-carboxylates, the structure of which was confirmed by X-ray diffraction analysis.

Sobre autores

E. Denislamova

Perm National Research Polytechnic University

Email: katherin85@rambler.ru

V. Lyadov

Perm National Research Polytechnic University

Email: katherin85@rambler.ru

D. Makrushin

Perm National Research Polytechnic University

Email: katherin85@rambler.ru

V. Ryabov

Perm National Research Polytechnic University

Email: katherin85@rambler.ru

M. Dmitriev

Perm State University

Email: katherin85@rambler.ru

A. Maslivets

Perm State University

Email: katherin85@rambler.ru

Bibliografia

  1. Машковский М.Д. Лекарственные средства. М.: Новая волна. 2011, 164-166.
  2. Рубцов А.Е., Махмудов Р.Р., Ковыляева Н.В., Просяник Н.И., Бобров А.В., Залесов В.В. Хим.-фарм.ж. 2002, 36, 31-35.
  3. Rubtsov A.E., Makhmudov R.R., Kovylyaeva N.V., Prosyanik N.I., Bobrov A.V., Zalesov V.V. Pharm. Chem. J. 2002, 36, 31-35. doi: 10.1023/A:1022669432631
  4. Рубцов А.Е., Залесов В.В. ЖОрХ. 2007, 43, 739-744.
  5. Rubtsov A.E., Zalesov V.V. Russ. J. Org. Chem. 2007, 43, 735-741. doi: 10.1134/S1070428007050156
  6. Масливец А.Н., Машевская И.В. 2,3-Дигидро-2,3-пирролдионы. Пермь: Пермский госуниверситет, 2005.
  7. Jayashree A., Narayana B., Uppine G.B., Ghate V.M., Lewis S.A., Prakash B., Kunhann S.B., Kumar M.S. J. Heterocycl. Chem. 2019, 56, 2398. doi. 10.1002/jhet.3627
  8. Червяков А.В., Дмитриев М.В., Масливец А.Н. ЖОрХ. 2018, 54, 801-803.
  9. Chervyakov A.V., Dmitriev M.V., Maslivets A.N. Russ. J. Org. Chem. 2018, 54, 807-809. doi: 10.1134/S1070428018050263
  10. Лядов В.А., Денисламова Е.С. Вест. Перм. Нац. Исслед. Политех. Универ. Хим. Технол. биотехнол. 2020, 4, 109. doi: 10.15593/2224-9400/2020.4.09
  11. CrysAlisPro, Agilent Technologies, Version 1.171.37.33 (release 27-03-2014 CrysAlis171.NET).
  12. Palatinus L., Chapuis G. J. Appl. Crystallogr. 2007, 40, 786-790. doi. 10.1107/S0021889807029238
  13. Sheldrick G.M. ActaCrystallogr., Sect. C. 2015, 71, 3-8. doi: 10.1107/S2053229614024218
  14. Dolomanov O.V., Bourhis L.J., Gildea R.J, Howard J.A.K., Puschmann H. J. Appl. Crystallogr. 2009, 42, 339-341. doi: 10.1107/S0021889808042726

Arquivos suplementares

Arquivos suplementares
Ação
1. JATS XML
Baixar

Declaração de direitos autorais © Russian Academy of Sciences, 2023