Semicarbazones of acetyldihydropyrans: diastereoselective acetylene-based two-step synthesis

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Abstract

2-Acetyl-3,4-dihydropyrans (diastereoselectively synthesized from acetylene and aromatic ketones in a one synthetic operation) reacted with semicarbazide hydrochloride to stereoselectively form semicarbazones of E -configuration in up to 86% yield.

About the authors

I. V Tatarinova

A.E. Favorsky Irkutsk Institute of Chemistry, Siberian Branch of the Russian Academy of Sciences

Email: boris_trofimov@irioch.irk.ru

N. A Lobanova

A.E. Favorsky Irkutsk Institute of Chemistry, Siberian Branch of the Russian Academy of Sciences

Email: boris_trofimov@irioch.irk.ru

I. A Ushakov

A.E. Favorsky Irkutsk Institute of Chemistry, Siberian Branch of the Russian Academy of Sciences

Email: boris_trofimov@irioch.irk.ru

E. Yu. Schmidt

A.E. Favorsky Irkutsk Institute of Chemistry, Siberian Branch of the Russian Academy of Sciences;Angarsk State Technical University

Email: boris_trofimov@irioch.irk.ru

B. A Trofimov

A.E. Favorsky Irkutsk Institute of Chemistry, Siberian Branch of the Russian Academy of Sciences

Email: boris_trofimov@irioch.irk.ru

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