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Calcium-Ion Binding by Polymeric Alendronate Derivatives
- Authors: Nekrasova Т.N.1, Fischer А.I.1, Nazarova O.V.1, Salikova E.P.1, Zolotova Y.I.1, Gavrilova I.I.1, Dobrodumov A.V.1, Bezrukova M.A.1, Panarin E.F.1
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Affiliations:
- Konstantinov Saint Petersburg Institute of Nuclear Physics of the Kurchatov Institute
- Issue: Vol 521, No 2 (2025)
- Pages: 20-24
- Section: CHEMISTRY
- URL: https://rjmseer.com/2686-9535/article/view/686892
- DOI: https://doi.org/10.31857/S2686953525020035
- EDN: https://elibrary.ru/IOZJFJ
- ID: 686892
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Abstract
Water-soluble phosphorus-containing polymers of various structures have been synthesized for the first time: a homopolymer of acryloyl alendronate, its copolymers with 4-acryloylmorpholine and 2-deoxy-2-methacrylamido-D-glucose, and a copolymer of N-vinylpyrrolidone with allyl alendronate. A comparative study of their ability to bind calcium ions has been conducted. It has been shown that for alendronate-containing polymers, the amount of Ca2+ bound by one phosphorus-containing group is 2 to 3 times higher than that of polyvinylphosphonic acid.
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About the authors
Т. N. Nekrasova
Konstantinov Saint Petersburg Institute of Nuclear Physics of the Kurchatov Institute
Author for correspondence.
Email: nazaro@hq.macro.ru
Russian Federation, Saint Petersburg
А. I. Fischer
Konstantinov Saint Petersburg Institute of Nuclear Physics of the Kurchatov Institute
Email: nazaro@hq.macro.ru
Russian Federation, Saint Petersburg
O. V. Nazarova
Konstantinov Saint Petersburg Institute of Nuclear Physics of the Kurchatov Institute
Email: nazaro@hq.macro.ru
Russian Federation, Saint Petersburg
E. P. Salikova
Konstantinov Saint Petersburg Institute of Nuclear Physics of the Kurchatov Institute
Email: nazaro@hq.macro.ru
Russian Federation, Saint Petersburg
Yu. I. Zolotova
Konstantinov Saint Petersburg Institute of Nuclear Physics of the Kurchatov Institute
Email: nazaro@hq.macro.ru
Russian Federation, Saint Petersburg
I. I. Gavrilova
Konstantinov Saint Petersburg Institute of Nuclear Physics of the Kurchatov Institute
Email: nazaro@hq.macro.ru
Russian Federation, Saint Petersburg
A. V. Dobrodumov
Konstantinov Saint Petersburg Institute of Nuclear Physics of the Kurchatov Institute
Email: nazaro@hq.macro.ru
Russian Federation, Saint Petersburg
M. A. Bezrukova
Konstantinov Saint Petersburg Institute of Nuclear Physics of the Kurchatov Institute
Email: nazaro@hq.macro.ru
Russian Federation, Saint Petersburg
E. F. Panarin
Konstantinov Saint Petersburg Institute of Nuclear Physics of the Kurchatov Institute
Email: nazaro@hq.macro.ru
Corresponding Member of the RAS
Russian Federation, Saint PetersburgReferences
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