Assessment of Human External Respiration Parameters in Simulated Lunar Gravity and Microgravity

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Abstract

The paper presents main results of experiments devoted to studying the influence of simulated microgravity and lunar gravity on the function of external respiration in humans. It has been shown that influence of human exposure to head-down bed rest (a model of the physiological effects of microgravity) and head-up bed rest (a model of the physiological effects of lunar gravity), similar to the influence of a horizontal position (bed rest), leads to a clinically insignificant decrease in the main respiratory parameters in the first hours of these analogue ground-based investigations. Subsequently, during hypokinesia, the marked changes are gradually levelled out. After cessation of experimental exposures, parameters of external respiration function are at the level of background values.

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About the authors

A. A. Puchkova

Institute of Biomedical Problems of the RAS

Author for correspondence.
Email: alina.a.puchkova@gmail.com
Russian Federation, Moscow

V. P. Katuntsev

Institute of Biomedical Problems of the RAS

Email: alina.a.puchkova@gmail.com
Russian Federation, Moscow

A. V. Shpakov

Institute of Biomedical Problems of the RAS

Email: alina.a.puchkova@gmail.com
Russian Federation, Moscow

D. M. Stavrovskaya

Institute of Biomedical Problems of the RAS

Email: alina.a.puchkova@gmail.com
Russian Federation, Moscow

G. K. Primachenko

Institute of Biomedical Problems of the RAS

Email: alina.a.puchkova@gmail.com
Russian Federation, Moscow

V. M. Baranov

Institute of Biomedical Problems of the RAS

Email: alina.a.puchkova@gmail.com
Russian Federation, Moscow

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2. Fig. 1. Relative changes in the main spirometric parameters obtained after 7 h of orthostatic (OH), anti-orthostatic (ANOG) and horizontal hypokinesia (HH) exposure. Bold font indicates the parameters GEF, FGEF, and SPEF1, the change of which after 7 h of experimental exposure reached the level of reliability (p < 0.05) compared to the background values in all three experimental models

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