Vol 20, No 3 (2017)

There has been presented an analysis of the contingent of persons suffered due to occupational diseases in the Russian Federation during 2015 year: results of the primary and repeated examination in the bureaus for the medical and social expertise, the structure of the primary and repeated disability in consideration of the age and groups of the disability. There have been formulated in detail the recommendations with respect to indicated and contraindicated conditions of labor in the main kinds of occupational diseases and poisonings.

There is proposed clinical expert and quantitative evaluation of persistent disorders of body functions with taking into account the TNM classification and prognostic factors in breast cancer patients.

Disability of the elderly age group of the population is the most important problem of public health and social services of all developed countries over the world without exception. In the Russian Federation, this age segment is characterized by the gain, reflecting the global process of population aging. The aim of the study was to analyze the nosological structure of the primary and secondary disability in elderly people in comparison with the main age categories of the adult population in the Russian Federation and the evaluation of rehabilitation / rehabilitation activities for disabled people. The volume of the study was 34,840,933 people aged of from 18 years and over, recognized as disabled, including the disabled elderly - 12,971,062. The subject of a special study was the nature of functional disorders, the degree of the disability, the nosological spectrum of causes of the disability of elderly people and the effectiveness of implemented measures of medical and social rehabilitation (rehabilitation and expert characterization). The study was selective, the sample size account of 370 people. The results of the research demonstrate the nosological structure of the pathology, the associated types of impairments and the nature of the disability to determine the severity of the disability in elderly people, the complexity of the formation and implementation of individual programs for the rehabilitation and rehabilitation of disabled people (IPRA). The improvement of the quality of life and integrating disabled people into the society has been and remains a difficult task for rehabilitation and habilitation activities. Rehabilitation and provision of technical means of rehabilitation, to a lesser extent - social and professional rehabilitation are the most feasible for the implementation.

Objectives of the study are the experimental study of the adaptational changes occurring in the animal organism against the background of intoxication induced by low doses of benzene and acetone. Material and methods. There were studied 45 white mice divided into three groups: 1st group was consisted of intact animals; 2nd group included animals exposed to benzene through inhalation at a concentration of 32,6 mg/l; 3rd group included animals exposed to acetone at a concentration of 99,0 mg/l. Animals were poisoned five times in special chambers. Eosinophil, neutrophil and lymphocyte blood count (absolute) was determined according to common procedures. Results and discussion. After general anesthesia the benzene poisoning for the first time resulted in statistically significant reduction of the body temperature by 7,7oC, while after the 5th poisoning procedure this index was reduced slightly. Upon the first poisoning procedure in the animals after their emergence from anesthesia the leukocyte count was reduced by 26,3%, while eosinophil, neutrophil and lymphocyte counts were reduced by 41,3, 87,6 and 62,8% accordingly. The neutrophil to lymphocyte ratio (neutrophil/lymphocyte) was reduced by 39,49%. Before the fifth poisoning procedure, relative to baseline values, the reduction in lymphocyte count amounted to 13,3%; in eosinophil, neutrophil and lymphocyte counts - to 40,0, 1,7 and 13,7% accordingly, while the neutrophil/lymphocyte radio was reduced by 18,9%. After the emergence of the animals from anesthesia of the fifth poisoning procedure, the changes observed in the above-mentioned indices were much less than the changes caused by the first poisoning. Thus, reduction in lymphocyte count amounted to 13,8%; in eosinophil, neutrophil and lymphocyte counts - to 18,3, 4,8 and 17,7% accordingly, while the neutrophil/lymphocyte radio was increased by 16,9%. The results of chronical acetone poisoning of the animals show that after one month from the beginning of the study, the number of neutrophils and monocytes was reduced due to the slight reduction in the quantity of eosinophils, neutrophils and lymphocytes. Conclusion. The shifts in the leukocytic response due to еру repeated exposure to petroleum products through inhalation may be considered as the intensification of protective reaction.

The posttraumatic stress disorder (PTSD) is no longer the pathology proper only to military men both over the world and in our country. At the present time there is observed a gain in PTSD patients. The disease has the negative impact both on the psychical and on somatic state of patients. The untimely and unqualified treatment of PTSD patients contributes to the chronicity of a pathologic process, results in social dysadaptation, prevents the return to the working activity. Doctors of very different specialities, most often neurologists, come into collision with PTSD. The article touches up the most urgent questions concerning PTSD, with the great attention paid to the differentiated diagnostics of the disease and methods of the treatment according to the achievements of the clinical practice. The methods of pharmacotherapy and psychotherapy of PTSD patients have been described on a contemporary level.